Tumoral Immune Suppression by Macrophages Expressing Fibroblast Activation Protein-α and Heme Oxygenase-1
نویسندگان
چکیده
منابع مشابه
Tumoral immune suppression by macrophages expressing fibroblast activation protein-α and heme oxygenase-1.
The depletion of tumor stromal cells that are marked by their expression of the membrane protein fibroblast activation protein-α (FAP) overcomes immune suppression and allows an anticancer cell immune response to control tumor growth. In subcutaneous tumors established with immunogenic Lewis lung carcinoma cells expressing ovalbumin (LL2/OVA), the FAP(+) population is comprised of CD45(+) and C...
متن کاملTumoral Immune Suppression by Macrophages Expressing Fibroblast Activation Protein-a and Heme Oxygenase-1
The depletion of tumor stromal cells that are marked by their expression of the membrane protein fibroblast activation protein-a (FAP) overcomes immune suppression and allows an anticancer cell immune response to control tumor growth. In subcutaneous tumors established with immunogenic Lewis lung carcinoma cells expressing ovalbumin (LL2/OVA), the FAPþ population is comprised of CD45þ and CD45 ...
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Aggressive tumors induce tumor-supporting changes in the benign parts of the prostate. One factor that has increased expression outside prostate tumors is hemoxygenase-1 (HO-1). To investigate HO-1 expression in more detail, we analyzed samples of tumor tissue and peritumoral normal prostate tissue from rats carrying cancers with different metastatic capacity, and human prostate cancer tissue s...
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ژورنال
عنوان ژورنال: Cancer Immunology Research
سال: 2013
ISSN: 2326-6066,2326-6074
DOI: 10.1158/2326-6066.cir-13-0150